Kisspeptin cell models from the hypothalamus
نویسندگان
چکیده
منابع مشابه
The roles of kisspeptin revisited: inside and outside the hypothalamus
Kisspeptin, encoded by KISS1/Kiss1 gene, is now considered a master regulator of reproductive functions in mammals owing to its involvement in the direct activation of gonadotropin-releasing hormone (GnRH) neurons after binding to its cognate receptor, GPR54. Ever since the discovery of kisspeptin, intensive studies on hypothalamic expression of KISS1/Kiss1 and on physiological roles of hypotha...
متن کاملNuclear Receptor LRH-1 Induces the Reproductive Neuropeptide Kisspeptin in the Hypothalamus
The differential expression and secretion of the neuropeptide kisspeptin from neurons in the arcuate (Arc) and anteroventral periventricular (AVPV) nuclei of the hypothalamus coordinate the temporal release of pituitary gonadotropins that control the female reproductive cycle. However, the molecular basis for this differential regulation is incompletely understood. Here, we report that liver re...
متن کاملEffects of light stress on the expression of Kisspeptin/GnRH in rat hypothalamus
Objective: This study aims to explore the effects of light stress on the expression of Kisspeptin/GnRH in rat hypothalamus. Methods: The rat model of chronic stress was established through artificial illumination time. The rats were divided into control group, continuous light group, interval light group and reverse day and night group randomly. The expression levels of Kisspeptin and GnRH in r...
متن کاملKisspeptin/Kisspeptin Receptor System in the Ovary
Kisspeptins are a family of neuropeptides that are critical for initiating puberty and regulating ovulation in sexually mature females via the central control of the hypothalamic-pituitary-gonadal axis. Recent studies have shown that kisspeptin and its receptor kisspeptin receptor (KISS1R) are expressed in the mammalian ovary. Convincing evidence indicates that kisspeptins can activate a wide v...
متن کاملImmunohistochemical characterization of the arcuate kisspeptin/neurokinin B/dynorphin (KNDy) and preoptic kisspeptin neuronal populations in the hypothalamus during the estrous cycle in heifers
Elucidating the physiological mechanisms that control reproduction is an obvious strategy for improving the fertility of cattle and developing new agents to control reproductive functions. The present study aimed to identify kisspeptin neurons in the bovine hypothalamus, clarifying that a central mechanism is also present in the cattle brain, as kisspeptin is known to play an important role in ...
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ژورنال
عنوان ژورنال: Frontiers in Neuroscience
سال: 2009
ISSN: 1662-453X
DOI: 10.3389/conf.neuro.03.2009.17.026